Cellular DNA content as a marker of human multiple myeloma

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Cellular DNA content as a marker of human multiple myeloma.

DNA flow cytometry of bone marrow cells from 61 patients with multiple myeloma in various stages of severity and treatment revealed a 65% incidence of aneuploidy. In the subgroup of 34 patients with plasmacytosis. 85% had aneuploid abnormalities. Of 50 patients with active disease. 76% had aneuploid bone marrow cells; conversely. 95% of patients with aneuploid abnormality had active multiple my...

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ژورنال

عنوان ژورنال: Blood

سال: 1980

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v55.3.403.403